Which medication is generally avoided during breastfeeding due to risk to the infant?

Acetaminophen

Ibuprofen

High-dose aspirin

When a mother breastfeeds, medications can pass into breast milk and affect the infant. High-dose aspirin is avoided because salicylates transfer into milk and can interfere with the baby’s blood clotting and GI lining; the risk increases with higher doses, making it unsuitable for nursing infants. In contrast, acetaminophen and ibuprofen are generally considered safe for short-term use during breastfeeding at typical doses. A product that combines acetaminophen with codeine is avoided because codeine can be converted to morphine in some babies, potentially causing sedation or respiratory problems.

Acetaminophen with codeine

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