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Multiple Choice

Methylergonovine (Methergine) is contraindicated in which condition?

Methergine is used after delivery to help the uterus contract and reduce hemorrhage, but it also causes strong vasoconstriction throughout the body. That vasoconstriction raises blood pressure, so giving it to someone who already has hypertension can lead to a dangerous spike in blood pressure, with risks such as hypertensive crisis or stroke. Because of this, hypertension is a contraindication. The other conditions listed don’t carry the same immediate risk from this drug’s vasoconstrictive effect. Hypotension isn’t a contraindication—the drug tends to raise BP. Diabetes and hyperkalemia don’t inherently contraindicate Methergine, though they require overall clinical consideration.

Methergine is used after delivery to help the uterus contract and reduce hemorrhage, but it also causes strong vasoconstriction throughout the body. That vasoconstriction raises blood pressure, so giving it to someone who already has hypertension can lead to a dangerous spike in blood pressure, with risks such as hypertensive crisis or stroke. Because of this, hypertension is a contraindication.

The other conditions listed don’t carry the same immediate risk from this drug’s vasoconstrictive effect. Hypotension isn’t a contraindication—the drug tends to raise BP. Diabetes and hyperkalemia don’t inherently contraindicate Methergine, though they require overall clinical consideration.